August - A paper from the Burgess Lab with Tim as first author has been published in Human Molecular Genetics. The paper entitled "A mouse model of autosomal dominant spastic ataxia and myopathy caused by a mutation in Tuba4a" can be found here: doi.org/10.1093/hmg/ddag084
July - Tim gave an invited talk entitled "Defining the role of the integrated stress response pathway in rare neuromuscular diseases" to the Division of Pharmacology and Pharmaceutical Sciences at University of Missouri Kansas City in Kansas City, MO.
June - Tim gave an invited talk entitled "Defining the role of the integrated stress response pathway in rare neuromuscular diseases" to the Molecular Neurobiology group at Radbout University and Donders Center for Neuroscience, Nijmegen, Netherlands.
June - Tim presented a poster at the Peripheral Nerve Society annual meeting in Maastricht, Netherlands.
May - A paper from Deanna Smith's lab at University of South Carolina with Tim as a co-author was accepted for publication in the Journal of Neuroscience. The paper entitled "LIS1 is critical for axon integrity in adult mice" can be found here: doi.org/10.1523/jneurosci.1971-25.2026
April - Tim gave an invited talk at the Frontiers in Molecular Medicine Research Symposium at UNC Chapel Hill in Chapel Hill, NC.
January - Tim gave an invited talk entitled "From mice to men: An integrated approach to studying rare neuromuscular diseases" to the Integrated Sciences Academy at Rochester Institute of Technology in Rochester, NY.
January - Tim has received a Seed Grant from the Merkin Peripheral Neuropathy and Nerve Regeneration Center for the project titled "Assessing ATF4 as a Therapeutic Target in tRNA Synthetase-Associated Forms of Charcot-Marie-Tooth Disease using human iPSCs". If successful, this 2-year project could lead to new treatments that protect peripheral nerves from damage in CMT by revealing how the stress-response protein ATF4 drives nerve injury. Using human stem cell–derived nerve cells, this research aims to identify molecular targets for intervention. Because ATF4 activation is shared across multiple peripheral nervous system disorders, these findings could ultimately benefit a broad patient community.
September - Tim gave an invited talk at Nationwide Children's Hospital in Columbus, OH.
September - A paper from the Burgess Lab entitled "SARM1 inhibition in three mouse models of Charcot-Marie-Tooth Disease" was accepted for publication in the Journal of the Peripheral Nervous System. See it here - doi.org/10.1111/jns.70053
September - An NIH "Re-training and re-tooling supplement" was awarded to Rob's R37 grant! Tim and Rob co-wrote this supplement to support Tim's training in generating and analyzing cutting-edge in vitro neuromuscular disease models with Drs. Alec Smith and Mark Bothwell at University of Washington.
June - Tim gave a talk and presented a poster at the Neurodegeneration Keystone meeting in Whistler, Canada.
May - Tim gave a talk at the Peripheral Nerve Society annual meeting in Edinburgh, Scotland.
April - Tim gave an invited talk at the Luxembour Institute for Systems Biomedicine in Esch-Sur-Alzette, Luxembourg.
February - Tim gave an invited talk to the Neuroscience Department at the University of Minnesota in the Twin Cities, MN.
February - Tim gave a talk and presented a poster at the Translation Control in Health and Disease GRS/GRC in Pomona, CA.
January - Tim gave an invited talk to the Center for Molecular Medicine and Genetics at Wayne State University in Detroit, MI .
November - Tim gave an invited talk entitled "An Integrated Approach to Studying Rare Neuromuscular Diseases" at the Annual Biomedical Research Conference for Minoritized Scientists (ABRCMS) in Pittsburgh, PA.
October - Tim presented a poster entitled "Biltong: An ENU-induced mouse model of autosomal dominant spastic ataxia" at the Society for Neuroscience (SfN) Annual Meeting in Chicago, IL.
October - A paper from the Cox lab at JAX entitled "Clinically relevant mouse models of severe Spinal Muscular Atrophy with Respiratory Distress type 1" was accepted for publication in Human Molecular Genetics. See it here - doi.org/10.1093/hmg/ddae116
August - Tim gave an invited talk entitled "The role of the integrated stress response in tRNA synthetase-associated Charcot-Marie-Tooth disease" at the University of Minnesota Medical School, Duluth Campus in Duluth, MN.
June - Tim gave a joint talk with Laura Morant from University of Antwerp entitled "Mechanisms and therapeutic strategies for tRNA synthetase associated CMTs" at the Peripheral Nerve Society (PNS) Annual Meeting in Montral, Canada.
June - Tim gave an invited talk entitled "ATF4 as a therapeutic target for Charcot-Marie-Tooth disease type 2D" at the Samuel M. Nabrit Conference for Early Career Scholars at Brown University in Providence, RI.
April - A paper from the Burgess Lab entitled "Testing Sipa1l2 as a modifier of CMT1A using mouse models" was accepted for publication in the Journal of Neuropathology & Experimental Neurology. See it here - doi.org/10.1093/jnen/nlae020
March - Tim gave a Spotlight Talk entitled "ATF4 as a therapeutic target for Charcot-Marie-Tooth disease type 2D" at the Discover BMB Annual Meeting in San Antonio, TX.
February - Tim gave an invited talk entitled "ATF4 as a therapeutic target for Charcot-Marie-Tooth disease type 2D" at the Charcot-Marie-Tooth Association Strategy To Accelerated Research (CMTA-STAR) Advisory Board Meeting in Dallas, TX.
January - Tim gave an invited talk on the "Best Journal of Anatomy Paper of 2022" entitled "Precision Mouse Models of Yars/Dominant Intermediate Charcot-Marie-Tooth Disease Type C and Sptlc1/Hereditary Sensory and Autonomic Neuropathy Type 1" at the Anatomical Society Winter Meeting in Liverpool, UK.